What is the definition of white matter?
: neural tissue especially of the brain and spinal cord that consists largely of myelinated nerve fibers bundled into tracts, has a whitish color, and typically underlies the cortical gray matter.
What is gray matter and white matter?
Grey matter is distinguished from white matter in that it contains numerous cell bodies and relatively few myelinated axons, while white matter contains relatively few cell bodies and is composed chiefly of long-range myelinated axons. The colour difference arises mainly from the whiteness of myelin.
What does it mean when you have white matter on a brain MRI?
Small strokes—the most common cause of white spots on a brain MRI—are often caused by blockages of small blood vessels due to high blood pressure and/or diabetes, while large strokes are usually caused by heart disease or carotid artery disease.
Is white matter bad?
More evidence has been accumulated that damage to cognitive areas is widespread from white matter disease. White matter disease is responsible for about a fifth of all strokes worldwide, more than doubles the future risk of stroke, and is a contributing factor in up to 45% of dementias.
What is the role of white matter?
White matter is found in the deeper tissues of the brain (subcortical). Myelin gives the white matter its color. It also protects the nerve fibers from injury. Also, it improves the speed and transmission of electrical nerve signals along extensions of the nerve cells called axons.
What is the life expectancy of someone with white matter disease?
It is not possible to stop disease progression, and it is typically fatal within 6 months to 4 years of symptom onset. People with the juvenile form of metachromatic leukodystrophy, which develops between the age of 4 and adolescence, may live for many years after diagnosis.
Is gray matter good or bad?
The gray matter changes occurred in the hippocampus, the part of the brain believed to be central to memory. It is “a structure important for healthy cognition across people’s lifespan,” the study says, and is “centrally involved in many functions including spatial navigation, episodic memory and stress regulation.”
What is the function of GREY matter?
What is the function of gray matter? Gray matter-heavy brain regions include those that control muscular and sensory activity. Cerebral cortex – The outer layer of the brain, the cerebral cortex, consists of columns of gray matter neurons, with white matter located underneath.
What is GREY matter disease?
“Gray matter disease causes progressive symptoms, like fatigue and memory loss. These higher brain functions are called cognitive functions. Most MS disability actually comes from cognitive dysfunction.”
What does it mean if you have white matter on your brain?
White matter disease is a disease that affects the nerves that link various parts of the brain to each other and to the spinal cord. These nerves are also called white matter. White matter disease causes these areas to decline in their functionality. This disease is also referred to as leukoaraiosis.
Can white matter lesions in the brain be nothing?
White matter lesions observed on brain MRI are usually characteristic and occur in specific areas including the corpus callosum and pons. “However, in many cases, the white matter lesions as isolated observations are nonspecific” and could be due to MS or another cause, explained Drs Lange and Melisaratos.
Does everyone have white matter in the brain?
R. Douglas Fields. “Gray matter” is only one of two types of brain tissue; the other “white matter” is rarely mentioned. Yet white matter makes up half the human brain and has not been thought to be important in cognition or learning outside the context of pathology.
How do you get rid of white matter disease?
There isn’t a specific treatment for white matter disease. The goal is to treat the cause of the damage and keep the disease from getting worse. Your doctor may prescribe medicines to lower your blood pressure or cholesterol.
Is white matter disease normal?
Originally, white matter disease was considered a normal, age-related change. But over the last decade, medical experts have come to understand that the presence of large areas of disease in the white matter of the brain are associated with cognitive decline and dementia in patients.
Does white matter disease cause headaches?
Patients with extensive white matter hyperintensities are likely to have tension-type headaches or to have headaches develop during middle age, according to results published in Cephalagia. Currently, there are no established treatments or strategies for managing white matter hyperintensities.