Often asked: What is myopathy?

What are the signs and symptoms of myopathy?

General signs and symptoms of myopathy include the following:

  • Symmetric proximal muscle weakness.
  • Malaise, fatigue.
  • Dark-colored urine (suggests myoglobinuria) and/or fever.
  • Absence of sensory complaints or paresthesias; however, deep tendon reflexes (DTRs) may be diminished/absent in hypokalemic paralysis.

What causes myopathy?

Most commonly, people develop acquired myopathy from muscle fatigue, electrolyte imbalance, or dehydration, resulting in stiffness or cramping. Other causes of myopathy include immune disorders that cause inflammation and pain.

What is the treatment for myopathy?

Supportive and symptomatic treatment may be the only treatment available or necessary for some disorders. Treatment for other disorders may include drug therapy, such as immunosuppressives, physical therapy, bracing to support weakened muscles, and surgery. The prognosis for individuals with a myopathy varies.

Does myopathy go away?

The chronic inflammatory myopathies can‘t be cured in most adults but many of the symptoms can be treated. Options include medication, physical therapy, and rest.

What does myopathy feel like?

Acquired myopathies may have symptoms similar to those of genetic myopathies and also may include: Muscle weakness. Muscle soreness (myalgias) Cramps.

How do you test for myopathy?


  1. Blood tests. These may be ordered to detect an enzyme called creatine kinase.
  2. Electromyography (EMG). Electromyography measures electrical activity within muscles.
  3. Genetic testing. This may be recommended to verify a particular mutation in a given gene.
  4. Muscle biopsy.

Does exercise help myopathy?

Exercise programmes to improve muscle strength, endurance and cardiovascular fitness have an important role in the overall management of patients with myopathy.

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Does myopathy get worse?

Unlike muscular dystrophies, myopathies usually don’t cause muscles to die but just keep them from working properly. Also, myopathies are usually nonprogres- sive — that is, a myopathy usually doesn’t grow worse over a person’s lifetime. In fact, some children with myopathies gain strength as they grow older.

What drugs can cause myopathy?

Direct myotoxicity – Examples include alcohol, cocaine, glucocorticoids, lipid-lowering drugs, antimalarials (which are associated with vacuolar myopathies), colchicine (which is associated with vacuolar myopathies), and zidovudine (which causes a mitochondrial myopathy).

Who gets myopathy?

Anyone can get a myopathy. Some develop at an early age, while other types develop later in life.

Who treats myopathy?

Patients with dermatomyositis, polymyositis, or necrotizing myopathy are usually treated by rheumatologists. Those with dermatomyositis may also work with a dermatologist. Those with IBM are often treated by neurologists.

How can you tell the difference between myopathy and neuropathy?

but in general it is a good thing to know about.

The College Answer from 2010.

Neuropathy Myopathy
CK level Normal Elevated
Nerve conduction Slowed Normal
EMG Fibrillations and fasciculations Small motor units
MRI Suble, near normal appearance Enhancement of affected muscle

What autoimmune disease causes leg pain?

Myositis (my-o-SY-tis) is a rare type of autoimmune disease that inflames and weakens muscle fibers. Autoimmune diseases occur when the body’s own immune system attacks itself. In the case of myositis, the immune system attacks healthy muscle tissue, which results in inflammation, swelling, pain, and eventual weakness.

How can you prevent myopathy?

There are no known ways to prevent myopathy. Muscle inflammation may be caused by an allergic reaction, exposure to a toxic substance or medicine, another disease such as cancer or rheumatic conditions, or a virus or other infectious agent.

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How does inflammatory myopathy affect the body?

General symptoms of chronic inflammatory myopathy include slow but progressive muscle weakness. Inflammation damages the muscle fibers, which causes weakness, and may affect the arteries and blood vessels that pass through muscle.

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